2010-05-18

DNA Robots: Spiders at the Nanoscale

Meet the nano-spiders: The DNA robots that could one day be walking through your body

Scientists have created microscopic robots out of DNA molecules that can walk, turn and even create tiny products of their own on a nano-scale assembly line.

The ground-breaking devices outlined in the journal Nature, could one day lead to armies of surgeon robots that could clean human arteries or build computer components.

In one of the projects a team from New York's Columbia University created a spider bot just four nanometres across. This is about 100,000 times smaller than the diameter of a human hair.

Columbia University Medical Center logo,Positioning Line Discover. Educate. Care. Lead.
Spiders at the Nanoscale: Molecules that Behave Like Robots

NEW YORK (May 12, 2010) - A team of scientists from Columbia University, Arizona State University, the University of Michigan, and the California Institute of Technology (Caltech) have programmed an autonomous molecular "robot" made out of DNA to start, move, turn, and stop while following a DNA track.

The development could ultimately lead to molecular systems that might one day be used for medical therapeutic devices and molecular-scale reconfigurable robots—robots made of many simple units that can reposition or even rebuild themselves to accomplish different tasks. A paper describing the work appears in the current issue of the journal Nature.






National Science FoundationPress Release 10-083
Molecular Robots On the Rise

Researchers announce new breakthrough in developing molecules that behave like robots



Researchers have created and observed a molecular robot capable of many steps, and of making decisions where to step and how long to stay. As the robot walks on the substrate, it changes each piece by cleaving off a part. If it touches a spot that has been cleaved already, it does not linger as long. The end of the track glows red and captures the robot, letting the researchers know when it has completed its walk. The robot glows green, allowing for the researchers to see it better.



In recent years, scientists have been working to create robots that consist of a single molecule. Until recently, these robots have been able of only brief, directed motion on a one-dimensional track. Now a team of researchers have successfully created molecular robots capable of simple robotic actions within a defined environment autonomously, including the ability to start moving, turn, and stop. The researchers believe the process they have developed to achieve these tentative first steps may allow for more complex robotic behavior from these tiny robots. Milan Stojanovich, representing team of researchers from four institutions, discusses the team's work and its potential for future progress in this new field.


RSC - Advancing the Chemical Sciences

Molecular robots on nano-assembly lines

[...]
Seeman and his team took their research in a different direction, developing a system in which a DNA walker travels along a path with three DNA 'modules' at fixed intervals in an assembly line arrangement. The modules hold a cargo of gold nanoparticles and are individually programmed to either donate or keep their cargo, so as the DNA walker passes by it can be loaded with cargo resulting in eight possible end products.

'I think of these DNA walkers as being similar to a chassis of a car rolling down the assembly line and we are adding components to it,' says Seeman.

[...]
Stojanovic described Seeman's nanoscale assembly line as a masterful example of non-autonomous robotics. He describes Seeman as 'like a micro-surgeon that slowly organises materials on this scale by adding DNA strands and taking them away. It's just beautiful work'.


Behold The First Nanobot Assembly Line In Action

On the left in the drawing above, you can see a diagram showing what's going on (click to enlarge), whereas on the right you can see an atomic force micrograph of the pieces of gold being gathered by the nanobot (you can't actually see the nanobot).


Sources
Meet the nano-spiders: The DNA robots that could one day be walking through your body | Mail Online
http://www.dailymail.co.uk/sciencetech/article-1278133/Meet-nano-spiders-The-DNA-robots-day-walking-body.html
Columbia University Medical Center Press Release
http://cumc.columbia.edu/news/press_releases/DNArobot.html
nsf.gov - Office of Legislative and Public Affairs (OLPA) News - Molecular Robots On the Rise - US National Science Foundation (NSF)
http://www.nsf.gov/news/news_summ.jsp?cntn_id=116957&org=OLPA&from=news
nsf.gov - News - Molecular Robots On the Rise- All Images - US National Science Foundation (NSF) - US National Science Foundation (NSF)
http://www.nsf.gov/news/news_images.jsp?cntn_id=116957&org=OLPA
Molecular robots on nano-assembly lines
http://www.rsc.org/chemistryworld/News/2010/May/12051003.asp
Behold The First Nanobot Assembly Line In Action - Nanotechnology - io9
http://io9.com/5538320/behold-the-first-nanobot-assembly-line-in-action?skyline=true&s=i

Related
BBC NEWS | Science/Nature | Molecular spiders grab nanograss
http://news.bbc.co.uk/2/hi/science/nature/5413658.stm
Spiders at the nanoscale: Molecules that behave like robots
http://www.eurekalert.org/pub_releases/2010-05/ciot-sat051110.php
Spiders at the nanoscale: Molecules that behave like robots
http://www.sciencedaily.com/releases/2010/05/100512131515.htm
Molecular robots on the rise (w/ Video)
http://www.physorg.com/news192968297.html
The rise of molecular robots - SmartPlanet
http://www.smartplanet.com/technology/blog/thinking-tech/the-rise-of-molecular-robots/4053/
Spiders at the nanoscale: Molecules that behave like robots (5/17/2010)
http://www.nanitenews.com/research/Spiders_at_the_nanoscale_Molecules_that_behave_like_robots.asp
Technology Review: DNA Robots on the Move
http://www.technologyreview.com/biomedicine/25287/?ref=rss&a=f
DNA nanobots can start, move, turn and stop while Following a DNA Track
http://nextbigfuture.com/2010/05/dna-nanobots-can-start-move-turn-and.html
Spiders at the Nanoscale: Molecules that Behave Like Robots - Caltech
http://media.caltech.edu/press_releases/13345
Milan N. Stojanovic
http://columbiamedicine2.org/CPET/people/milan.html
Ned Seeman's Home Page
http://seemanlab4.chem.nyu.edu/
Walter Lab
http://www.umich.edu/~rnapeopl/WalterSummarySpider.htm
Home | The Yan Lab
http://labs.biodesign.asu.edu/yan/
Computer Science, Caltech - Erik Winfree
http://www.cs.caltech.edu/cspeople/faculty/winfree_e.html
Access : Molecular robots guided by prescriptive landscapes : Nature
http://www.nature.com/nature/journal/v465/n7295/full/nature09012.html
Access : A proximity-based programmable DNA nanoscale assembly line : Nature
http://www.nature.com/nature/journal/v465/n7295/full/nature09026.html