2008-10-18

Green Fluorescent Protein (GFP) -- Making the Invisible Visible


The Nobel Prize in Chemistry 2008 is shared by Osamu Shimomura, Woods Hole, Martin Chalfie, and Roger Y. Tsien for the discovery and development of the green fluorescent protein, GFP.
The Academy noted that "this protein has become one of the most important tools used in contemporary bioscience. With the aid of GFP, researchers have developed ways to watch processes that were previously invisible, such as the development of nerve cells in the brain or how cancer cells spread."
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The GFP Site
aequorea
Green Fluorescent Protein (GFP) has existed for more than one hundred and sixty million years in one species of jellyfish, Aequorea victoria. The protein is found in the photoorgans of Aequorea,
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clipped from www.conncoll.edu


In 1994 GFP was cloned. Now GFP is found in laboratories all over the world where it is used in every conceivable plant and animal. Flatworms, algae, E. coli and pigs have all been made to fluoresce with GFP.


The importance of GFP was recognized in 2008 when the Nobel Committee awarded Osamu Shimomura, Marty Chalfie and Roger Tsien the Chemistry Nobel Prize
"for the discovery and development of the green fluorescent protein, GFP".

clipped from nobelprize.org
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Nobel Prize® medal - registered trademark of the Nobel Foundation

The Nobel Prize in Chemistry 2008


Glowing proteins – a guiding star for biochemistry

clipped from tsienlab.ucsd.edu
http://tsienlab.ucsd.edu/Images/General/IMAGE-%20Composite.jpg
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A Green Light for Biology -- Making the Invisible Visible

The protein, found in jellyfish helps researchers track substances of all kinds, in real time, and show how they mark cells, maintain them and function in concert with other cells.

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Related:
Green Fluorescent Protein - The GFP Site
The Nobel Prize in Chemistry 2008 - Press Release
Green fluorescent protein - Wikipedia, the free encyclopedia
Tsien lab Website
The Nobel Prize in Chemistry 2008: Jellyfish and Green Fluorescence - Medgadget - www.medgadget.com