2008-07-22

Monitoring Health Through Music of the Genes

Future doctors could monitor health through music of the patients' genes by using a new method where gene expressions, the process by which a gene's DNA sequence is converted into the functional proteins of a cell, are transformed into into musical sounds. In the acoustic translation, harmony represents good health, and discord indicates disease.
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Future doctors could monitor health through music of the patients' genes

In this representation of genetic activity, the circles are genes, the lines signify relationships, and colors indicate genes that have similar functions.
In this representation of genetic activity, the circles are genes, the lines signify relationships, and colors indicate genes that have similar functions.
They use mathematical techniques, in the case of colon cancer, for instance, to reduce the data from a group of nearly 10,000 genes down to just four combinations that they say represent virtually all the variability in the data.
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Discovering Biological Guilds Through Topological Abstraction
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Each combination is then assigned a note. When three or more notes are played at the same time, they become a chord. When those chords are played across time, they become music.
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The researchers assign a harmonious sound to a normal, healthy gene network. When there are deviations in the genes' behavior -- such as the presence of disease -- the music sounds inharmonious.
Technology Review - Published By MIT
Multimedia
Listen to examples of gene-based music.

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Related:
Future doctors could monitor health through music of the patients' genes - The Boston Globe
Musical Gene Expression: A 4-D Exhibition of Interaction and Expression
Technology Review: A Musical Score for Disease
The Harvard Crimson :: News :: TF Translates DNA Into Music Sequence
Music Used to Analyze Gene Expression - Medgadget - www.medgadget.com